Peptide Database

Peptide NameCoagulation factor VII human

Function Ontology

Hemostasis ▸ Anticoagulant activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length466 amino acids

Chemical FormulaC2256H3545N653O672S32

DescriptionStandard

        MVSQALRLLCLLLGLQGCLAAGGVAKASGGETRDMPWKPGPHRVFVTQEEAHGVLHRRRRANAFLEELRPGSLERECKEEQCSFEEAREIFKDAERTKLFWISYSDGDQCASSPCQNGGSCKDQLQSYICFCLPAFEGRNCETHKDDQLICVNENGGCEQYCSDHTGTKRSCRCHEGYSLLADGVSCTPTVEYPCGKIPILEKRNASKPQGRIVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHDLSEHDGDEQSRRVAQVIIPSTYVPGTTNHDIALLRLHQPVVLTDHVVPLCLPERTFSERTLAFVRFSLVSGWGQLLDRGATALELMVLNVPRLMTQDCLQQSRKVGDSPNITEYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQGCATVGHFGVYTRVSQYIEWLQKLMRSEPRPGVLLRAPFP
    

Molecular Weight51593.33 Da

Isoelectric Point (pI)6.92

Net Charge (pH 7.0)-0.37

Net Charge (pH 7.4) -1.84

Charge Density (pH 7.0) -0.0008

GRAVY Index-0.29

Hydrophobic Moment 0.80

Boman Index-0.01

Instability Index48.68

Aliphatic Index 79.27

Aromaticity 0.0751

Extinction Coeff. Reduced 67380.00

Extinction Coeff. Oxidized 69005.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056773 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyCoagulation factor

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Coagulation factor replacement Enzyme replacement

Half-Life5 h

RECORD: Rec_0358109 VERIFIED: NO