Peptide Database

Peptide NameDefensin alpha 5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC422H700N132O142S7

DescriptionStandard

        MRTITILAAILLVALQAQAESLQERADEATTQKQSGEDNQDLAISFAGNGLSALRTSGSQARATCYCRTGPCTNRESLSGVCEISGRLYRFCCR
    

Molecular Weight10119.33 Da

Isoelectric Point (pI)7.56

Net Charge (pH 7.0)0.46

Net Charge (pH 7.4) 0.14

Charge Density (pH 7.0) 0.0049

GRAVY Index-0.19

Hydrophobic Moment 0.68

Boman Index-0.06

Instability Index36.26

Aliphatic Index 81.17

Aromaticity 0.0426

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4494.92

LogP -60.06

H-bond Donors 166.0

H-bond Acceptors 150.0

Rotatable Bonds 343.0

Heavy Atoms 703.0

Ring Count 5.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0015047 VERIFIED: YES

Provenance & Taxonomy

OrganismGorilla gorilla gorilla [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9595

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic

RECORD: Rec_0032964 VERIFIED: NO