Peptide Database

Peptide NameMedusin-PT1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC86H156N20O21S

DescriptionStandard

        LLGMIPVAIKAISALSKL
    

Molecular Weight1838.34 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0977

GRAVY Index1.60

Hydrophobic Moment 0.51

Boman Index0.51

Instability Index9.11

Aliphatic Index 184.44

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 641.73

LogP -2.19

H-bond Donors 22.0

H-bond Acceptors 24.0

Rotatable Bonds 62.0

Heavy Atoms 128.0

Ring Count 1.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390981 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa tarsius [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli

Activity128 μg/mL

MethodMIC

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