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MYP_168276
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Basic Information
Casein alpha-s2 [164-179]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Enzyme modulation ▸ Enzyme inhibition ▸ Phosphodiesterase inhibition ▸ CaMPDE inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C95H151N25O23
Standard
Sequence
LKKISQRYQKFALPQY
Physicochemical Analysis
2011.37 Da
10.17
3.76
3.54
0.2347
-0.94
0.68
-0.24
25.45
79.38
0.1875
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
820.95
-5.09
28.0
27.0
68.0
143.0
4.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0120358 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory
Calmodulin-dependent cyclic nucleotide phosphodiesterase
38 μM
IC50
RECORD: Rec_0153616 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperRecio I., Visser S. Identification of two distinct antibacterial domains within the sequence of bovine alpha(s2)- casein. Biochim. Biophys. Acta. Vol. 1428, s. 314-326.
RECORD: Rec_0184190 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
PaperRecio I., Visser S.. Identification of two distinct antibacterial domains within the sequence of bovine alphas2-casein.Biochim. Biophys. Acta, 1428 (1999) 314-326.
RECORD: Rec_0256095 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0329122 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Campde Inhibitor
PaperKizawa A., Nagamura K., Murakami U.. Calmodulin-binding peptides isolated from alpha-casein peptone. J. Dairy Res., 62, 587-592, 1995.
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