Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length162 amino acids

Chemical FormulaC788H1250N230O230S3

DescriptionStandard

        MAVITPQQAGGKNVCAFLDMIAYSEGTDNGRQRTNDHGYDVLVGGGLFTGYADHPRKLVELPKLGIKSTAAGRYQLLSRYYDAYKKQLGLKDFSPLSQDLIAIQQIRERRALPLIQAGQFEQAVRQVRNIWASLPGAGYGQHEQKIANLLAAYRNAGGTVAA
    

Molecular Weight17721.95 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.34

Charge Density (pH 7.0) 0.0355

GRAVY Index-0.32

Hydrophobic Moment 0.82

Boman Index0.00

Instability Index31.13

Aliphatic Index 89.26

Aromaticity 0.0864

Extinction Coeff. Reduced 18910.00

Extinction Coeff. Oxidized 18910.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7458.10

LogP -76.48

H-bond Donors 257.0

H-bond Acceptors 242.0

Rotatable Bonds 591.0

Heavy Atoms 1251.0

Ring Count 24.0

Amide Bonds 181.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0319787 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage vB_EcoM_ECO1230-10 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic