Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC481H788N126O128S7

DescriptionStandard

        MKLFLVLIILLFEVLTDGARLKKCFNNITGYCRKKCKVGEIHEIGCLSGKLCCVNDEENKKHVPVKKPHQHPVEKLSVQQDYVILPTITIFTV
    

Molecular Weight10608.62 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.80

Net Charge (pH 7.4) 4.26

Charge Density (pH 7.0) 0.0516

GRAVY Index0.10

Hydrophobic Moment 0.62

Boman Index0.07

Instability Index32.60

Aliphatic Index 111.94

Aromaticity 0.0645

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4075.52

LogP -28.43

H-bond Donors 143.0

H-bond Acceptors 144.0

Rotatable Bonds 362.0

Heavy Atoms 742.0

Ring Count 14.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0222617 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinopithecus roxellana [Animal]

FamilyDefensin

Tax ID61622

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence