Peptide Database

Peptide NameAlyteserin-2a [A10W, N15K]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC82H141N19O20

DescriptionStandard

        ILGKLLSTAWGLLSKL
    

Molecular Weight1713.11 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.1099

GRAVY Index1.08

Hydrophobic Moment 0.41

Boman Index0.42

Instability Index-0.99

Aliphatic Index 176.88

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 628.34

LogP -2.38

H-bond Donors 23.0

H-bond Acceptors 22.0

Rotatable Bonds 58.0

Heavy Atoms 121.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0255991 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

FamilyAlyteserin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

TargetHuman erythrocytes

Activity6 μM

MethodHemolysis

RECORD: Rec_0296637 VERIFIED: YES