Peptide Database

Peptide NameBombinins BLP-7 H-BO [Cleaved into: Bombinin-like peptide 7 (BLP-7); Bombinin H-BO]

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC679H1116N194O210S3

DescriptionStandard

        MNFKYIIAVSFLIASTYARSVKNDEQSLSQRDVLDEESLREIRGIGGALLSAGKSALKGLAKGLAEHFANGKRTAEEHEVMKRLEAVMRDLDSLDHPEEASEKETRGFNQEEIANLFTKKEKRIIGPVLGLIGKALGGLLG
    

Molecular Weight15453.49 Da

Isoelectric Point (pI)6.33

Net Charge (pH 7.0)-1.20

Net Charge (pH 7.4) -1.62

Charge Density (pH 7.0) -0.0085

GRAVY Index-0.32

Hydrophobic Moment 0.65

Boman Index-0.04

Instability Index38.17

Aliphatic Index 96.95

Aromaticity 0.0496

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6564.12

LogP -64.93

H-bond Donors 228.0

H-bond Acceptors 215.0

Rotatable Bonds 545.0

Heavy Atoms 1086.0

Ring Count 12.0

Amide Bonds 148.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0293216 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina orientalis [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Yeast Anti-Gram-negative Anti-Gram-positive Anticancer Hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0333171 VERIFIED: YES