Peptide Database

Peptide NameC-flanking peptide of NPY

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC166H243N51O50

DescriptionStandard

        GKRGDSFRKREFFRTNGERYPEDAAAWTEFQ
    

Molecular Weight3753.02 Da

Isoelectric Point (pI)8.49

Net Charge (pH 7.0)0.77

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0249

GRAVY Index-1.58

Hydrophobic Moment 0.48

Boman Index-0.42

Instability Index34.05

Aliphatic Index 9.68

Aromaticity 0.1935

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1695.76

LogP -18.08

H-bond Donors 61.0

H-bond Acceptors 51.0

Rotatable Bonds 124.0

Heavy Atoms 267.0

Ring Count 8.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0008784 VERIFIED: NO

Provenance & Taxonomy

OrganismAplysia californica [Animal]

FamilyNPY

Tax ID6500

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

NPY-family Neuropeptide Neuromodulator

RECORD: Rec_0136316 VERIFIED: NO

Provenance & Taxonomy

OrganismAplysia californica [Animal]

FamilyC-flanking peptide of NPY

Tax ID6500

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0232992 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

RECORD: Rec_0295330 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/