Peptide Database

Peptide NameNukacin ISK-1

Function Ontology

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Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC130H191N35O36S4

DescriptionStandard

        KNGVFKTISHECHMNSWQFLFTCCS
    

Molecular Weight2948.38 Da

Isoelectric Point (pI)7.97

Net Charge (pH 7.0)0.91

Net Charge (pH 7.4) 0.55

Charge Density (pH 7.0) 0.0362

GRAVY Index-0.12

Hydrophobic Moment 0.41

Boman Index0.09

Instability Index25.18

Aliphatic Index 42.80

Aromaticity 0.1600

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1154.63

LogP -11.78

H-bond Donors 43.0

H-bond Acceptors 43.0

Rotatable Bonds 95.0

Heavy Atoms 205.0

Ring Count 7.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0311427 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus suis [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)