Peptide Database

Peptide NamePrecursor of antifungal peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC70H127N17O13

DescriptionStandard

        KKLFKKILKVLG
    

Molecular Weight1414.86 Da

Isoelectric Point (pI)10.60

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.54

Charge Density (pH 7.0) 0.3963

GRAVY Index0.25

Hydrophobic Moment 0.84

Boman Index-0.02

Instability Index-15.61

Aliphatic Index 154.17

Aromaticity 0.0833

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 513.52

LogP 0.09

H-bond Donors 18.0

H-bond Acceptors 18.0

Rotatable Bonds 54.0

Heavy Atoms 100.0

Ring Count 1.0

Amide Bonds 11.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0025515 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetFusarium oxysporum; Penicillium expansum; Aspergillus niger; Rhizopus stolonifer

MethodMIC

PaperBadosa E., Ferr¨¦ R., Franc¨¦s J., Bardaj¨ª E., Feliu L., Planas M., Montesinos E.. Sporicidal activity of synthetic antifungal undecapeptides and control of Penicillium rot of apples. Applied and Environmental Microbiology, 75, 5563-5569, 2009. PMID19617390 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19617390/

RECORD: Rec_0249081 VERIFIED: YES