Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length391 amino acids

Chemical FormulaC1927H3074N520O556S13

DescriptionStandard

        GGVVESCSPCVPAAQQQGIAILEKELAQLKLPDISGKSGKVRYSFSSCEADSRSLLQALSLTNISFLSPSPCSRGHGSFNLKVENVYMKIILRLGSDTTGKPTISTSDCSARISKVRVRFSGKLGWLYNLFHRVIESKLRKNLERKVCDNVAKSVQNELQKQVRTLPVTARIDDKIGIDYSLVAPPRATAHSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHERMVYFGASSYFFNTAGIAYHKAGALVFEITEAMIPKESEFGLDTSAFSAFIPQLEEMYPNMPMKFRLSTPTAPFLTIGPGGISFQPIVDVQAYAILPNSSLAPLFLLSLVRNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGHFQVQFLQTIMNYLTSSILLPRLN
    

Molecular Weight42839.02 Da

Isoelectric Point (pI)9.36

Net Charge (pH 7.0)11.34

Net Charge (pH 7.4) 10.61

Charge Density (pH 7.0) 0.0290

GRAVY Index0.05

Hydrophobic Moment 0.69

Boman Index0.08

Instability Index40.63

Aliphatic Index 97.01

Aromaticity 0.0844

Extinction Coeff. Reduced 21890.00

Extinction Coeff. Oxidized 22265.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0376754 VERIFIED: NO

Provenance & Taxonomy

OrganismVidua macroura [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria