Peptide Database

Peptide NameCecropin-B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC305H504N90O83S2

DescriptionStandard

        MNFNKIFVFMALILAISLGNTEAGWLRKLGKKIERIGQHTRDASIQVLGIAQQAANVAATARG
    

Molecular Weight6823.95 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)4.59

Net Charge (pH 7.4) 4.31

Charge Density (pH 7.0) 0.0729

GRAVY Index0.23

Hydrophobic Moment 0.98

Boman Index0.13

Instability Index23.12

Aliphatic Index 110.16

Aromaticity 0.0635

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2821.44

LogP -26.60

H-bond Donors 98.0

H-bond Acceptors 91.0

Rotatable Bonds 235.0

Heavy Atoms 480.0

Ring Count 6.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0214493 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila mauritiana [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence