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MYP_168009
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Basic Information
Com5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
6 amino acids
C49H67N17O7
Standard
Sequence
RRWWRF
Physicochemical Analysis
1006.17 Da
12.00
2.76
2.56
0.4600
-2.08
1.14
-0.80
199.27
0.00
0.5000
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
426.10
-0.70
18.0
10.0
29.0
73.0
5.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0324683 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Amidation
Bio-Activity Profile
Antimicrobial Anti-Gram-positive
Bacillus subtilis
1.9 μM
LD99.99
Human serum, in vitro; ~5400 s
PaperSerum stabilities of short tryptophan- and arginine-rich antimicrobial peptide analogs PMID20844765 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20844765/
RECORD: Rec_0324961 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
No specific N-terminal
No specific C-terminal
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
6.3 μM
MIC
PMID16075425;7883644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16075425/
RECORD: Rec_0338077 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
No specific N-terminal
No specific C-terminal
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID16075425;7883644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16075425/
RECORD: Rec_0341936 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
No specific N-terminal
No specific C-terminal
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
PMID16075425;7883644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16075425/
RECORD: Rec_0348055 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-positive Anti-Gram-negative
PMID7883644 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7883644/
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