Peptide Database

Peptide NameColicin-B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC461H739N131O153S

DescriptionStandard

        MSSNNHDVIVRFPEGSGVSPLYISAVDILDSNSLSQRQEAENNAKDDFRVKKEQENYEKTVLTKTSEVIISVGDKVGEYLGDNTRHFPVKLQRI
    

Molecular Weight10596.65 Da

Isoelectric Point (pI)5.30

Net Charge (pH 7.0)-3.31

Net Charge (pH 7.4) -3.65

Charge Density (pH 7.0) -0.0352

GRAVY Index-0.65

Hydrophobic Moment 0.57

Boman Index-0.13

Instability Index39.15

Aliphatic Index 83.83

Aromaticity 0.0638

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4669.65

LogP -53.31

H-bond Donors 159.0

H-bond Acceptors 153.0

Rotatable Bonds 363.0

Heavy Atoms 746.0

Ring Count 11.0

Amide Bonds 104.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0402689 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)