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MYP_167990
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Basic Information
Gaduscidin-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
21 amino acids
C116H176N38O23
Standard
Sequence
FIHHIIGWISHGVRAIHRAIH
Physicochemical Analysis
2470.88 Da
12.00
2.20
1.74
0.1046
0.48
0.82
0.30
49.01
134.76
0.0952
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
948.54
-4.36
35.0
30.0
77.0
177.0
8.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042888 VERIFIED: YES
Provenance & Taxonomy
Gadus morhua [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli MG1655
2 μM
MBC
PMID33770667;33428273 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33770667/
RECORD: Rec_0117389 VERIFIED: YES
Provenance & Taxonomy
Gadus morhua [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
PMID33770667;33428273 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33770667/
RECORD: Rec_0155770 VERIFIED: YES
Provenance & Taxonomy
Gadus morhua [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio harveyi
8 μM
MIC
PMID33770667;33428273 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33770667/
RECORD: Rec_0173650 VERIFIED: YES
Provenance & Taxonomy
Gadus morhua [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa PAO1
64 μM
MIC
PMID33770667;33428273 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33770667/
RECORD: Rec_0175319 VERIFIED: YES
Provenance & Taxonomy
Atlantic cod [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
55.56% similar to AP3117 (Greater amberjack piscidin). I: 29%; H: 24%; A=G=R: 10%. Chemical modification: the last Glycine can be converted to C-terminal amidation (e.g., GAD-1) (McDonald M et al., 2015)
Bio-Activity Profile
Antimicrobial Anticancer
Escherichia coli ATCC 25922, Vibrio anguillarum NCIMB 2133, Vibrio anguillarum NCIMB 2129, Y. ruckeric NCIMB 2196, Y. ruckeric VI-3629, and P. immobilisc NCIMB 308
0.3-10 μM
MIC
PaperDifferential expression and biological activity of two piscidin paralogues and a novel splice variant in Atlantic cod (Gadus morhua L.)
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