Peptide Database

Peptide NameDPV7b

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC86H166N36O19

DescriptionStandard

        GKRKKKGKLGKKRPRSR
    

Molecular Weight2008.47 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)10.75

Net Charge (pH 7.4) 10.54

Charge Density (pH 7.0) 0.6325

GRAVY Index-2.65

Hydrophobic Moment 0.40

Boman Index-1.07

Instability Index66.86

Aliphatic Index 22.94

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 970.10

LogP -11.45

H-bond Donors 37.0

H-bond Acceptors 30.0

Rotatable Bonds 79.0

Heavy Atoms 141.0

Ring Count 1.0

Amide Bonds 16.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0011370 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available

RECORD: Rec_0022253 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDPV

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCysteine addition

C-TermNone

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0060433 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0064626 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDPV/CAP37-derived

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition for conjugation

C-TermNone

Other ModsN-term detail: Cys added to N -terminus for conjugation of report

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHeLa; HCT116; HL-60; K562; Molt4; NIH-3T3; primary hepatocyte cultures

MethodCellular uptake assay

RECORD: Rec_0418489 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermCys addition

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic