Peptide Database

Peptide NameCL-defensin

Function Ontology

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Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC193H306N66O53S6

DescriptionStandard

        ATCDLFSFQSKWVTPNHAACAAHCLLRGNRGGRCKGTICHCR
    

Molecular Weight4591.29 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)5.00

Net Charge (pH 7.4) 4.57

Charge Density (pH 7.0) 0.1190

GRAVY Index-0.18

Hydrophobic Moment 0.58

Boman Index-0.06

Instability Index38.97

Aliphatic Index 55.95

Aromaticity 0.0714

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1916.82

LogP -24.14

H-bond Donors 75.0

H-bond Acceptors 67.0

Rotatable Bonds 147.0

Heavy Atoms 318.0

Ring Count 8.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0382496 VERIFIED: YES

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)