‹ ›
MYP_167926
← PREVIOUS NEXT → BACK
Basic Information
Clavanin-A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C131H184N34O27
Standard
Sequence
VFQFLGKIIHHVGNFVHGFSHVF
Physicochemical Analysis
2667.07 Da
8.75
1.08
0.67
0.0470
0.78
0.64
0.46
-14.16
101.30
0.2174
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
950.67
-3.94
32.0
32.0
83.0
192.0
9.0
24.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0198466 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Clavanin-A
7725
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antileishmanial Anti-Trypanosoma cruzi
Trypanosoma cruzi
65.9 μM
LD50; MTT assay
PMID17888907 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17888907/
RECORD: Rec_0231305 VERIFIED: YES
Provenance & Taxonomy
Sea squirt [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID4303114 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4303114/
RECORD: Rec_0242586 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
allo-residue reported
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus 930918-3 or ATCC 30371 or 28841 or MRSA, Enterococcus faecalis CDC 21, Listeria monocytogenes EGD
0.2-3.8 μg/mL
MIC
PaperClavanins, alpha-helical antimicrobial peptides from tunicate hemocytes.
RECORD: Rec_0250115 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal
yeast Candida albicans
PaperPubMed PMID: 9001389 | PubMed PMID: 9237689 PMID9001389;9237689 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9001389/
RECORD: Rec_0262596 VERIFIED: YES
Provenance & Taxonomy
Styela clava [Animal]
Clavanin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
64 μM
MIC
PMID28226206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28226206/
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records on this page · Page 3 of 5