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MYP_167922
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Basic Information
Mastoparan-C [L1G, A5K]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
14 amino acids
C71H133N19O16
Standard
Sequence
GNLKKLLAVAKKIL
Physicochemical Analysis
1508.93 Da
10.48
3.76
3.55
0.2683
0.57
0.64
0.12
-1.21
174.29
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
588.79
-2.35
20.0
20.0
56.0
106.0
0.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018977 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
mouse erythrocytes
PaperNewly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0019634 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae ATCC 700603
16 μM
MIC
PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0022840 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis ATCC 23857
4 μM
MIC
PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0029514 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Mastoparan
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
16 μM
MIC
PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
RECORD: Rec_0111001 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922(150mM NaCl
16 μM
MIC
PaperNewly designed antimicrobial peptides with potent bioactivity and enhanced cell selectivity prevent and reverse rifampin resistance in Gram-negative bacteria PMID33285267 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33285267/
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