Peptide Database

Peptide NameLysozyme

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length131 amino acids

Chemical FormulaC649H1028N192O186S9

DescriptionStandard

        GIWTICRGATVVDGKTVFPNMKLSKEKCDQVNAIERDKALAWVERNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQVIRRDQESALTCWGIEQ
    

Molecular Weight14784.87 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)7.69

Net Charge (pH 7.4) 7.34

Charge Density (pH 7.0) 0.0587

GRAVY Index-0.50

Hydrophobic Moment 0.70

Boman Index-0.10

Instability Index50.65

Aliphatic Index 70.76

Aromaticity 0.0916

Extinction Coeff. Reduced 31970.00

Extinction Coeff. Oxidized 32470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6162.15

LogP -62.41

H-bond Donors 223.0

H-bond Acceptors 203.0

Rotatable Bonds 492.0

Heavy Atoms 1036.0

Ring Count 23.0

Amide Bonds 142.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0209861 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli MS 124-1 [Bacterium]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic Non-ribosomal

MethodQualitative functional evidence