Peptide Database

Peptide NameDermaseptin-B9

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC380H617N99O127S3

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSVCEEEKRENEDEEEQEDDEQSEEKRALWKTIIKGAGKMIGSLAKNLLGSQAQPESEQ
    

Molecular Weight8700.75 Da

Isoelectric Point (pI)4.55

Net Charge (pH 7.0)-7.47

Net Charge (pH 7.4) -7.74

Charge Density (pH 7.0) -0.0971

GRAVY Index-0.56

Hydrophobic Moment 0.66

Boman Index-0.09

Instability Index78.38

Aliphatic Index 88.70

Aromaticity 0.0519

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3711.45

LogP -35.00

H-bond Donors 125.0

H-bond Acceptors 123.0

Rotatable Bonds 313.0

Heavy Atoms 609.0

Ring Count 6.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173132 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa bicolor [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Anti-Mollicute Non-hemolytic Non-ribosomal

MethodQualitative functional evidence