Peptide Database

Peptide NamePENK(238-259)

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Neuromodulation

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC112H161N23O43S

DescriptionStandard

        FAEFLPSDEEGESYSKEVPEME
    

Molecular Weight2549.67 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-7.22

Net Charge (pH 7.4) -7.44

Charge Density (pH 7.0) -0.3280

GRAVY Index-1.00

Hydrophobic Moment 0.43

Boman Index-0.06

Instability Index63.85

Aliphatic Index 35.45

Aromaticity 0.1364

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1062.18

LogP -9.23

H-bond Donors 34.0

H-bond Acceptors 37.0

Rotatable Bonds 83.0

Heavy Atoms 179.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0144108 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyOpioid

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid Analgesic Neuromodulator