Peptide Database

Peptide NameDefensin alpha 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length97 amino acids

Chemical FormulaC449H745N141O145S7

DescriptionStandard

        MRTLAILAAILLVALQVQAESLQERADEATTQEQPGEDDQDFAVSFEENGLSTLKASGSRARIICHCQIGRCSRPESYSRICILHGQVARLCCRRAS
    

Molecular Weight10663.03 Da

Isoelectric Point (pI)6.08

Net Charge (pH 7.0)-1.36

Net Charge (pH 7.4) -1.78

Charge Density (pH 7.0) -0.0140

GRAVY Index-0.15

Hydrophobic Moment 0.57

Boman Index-0.07

Instability Index51.01

Aliphatic Index 92.68

Aromaticity 0.0309

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4660.35

LogP -55.52

H-bond Donors 170.0

H-bond Acceptors 153.0

Rotatable Bonds 363.0

Heavy Atoms 742.0

Ring Count 7.0

Amide Bonds 105.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0146647 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyDefensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic Non-ribosomal