‹ ›
MYP_167854
← PREVIOUS NEXT → BACK
Basic Information
r8-BadBH3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
34 amino acids
C187H311N75O48S
Standard
Sequence
RRRRRRRRGNLWAAQRYGRELRRMSDEFVDSFKK
Physicochemical Analysis
4410.01 Da
12.00
9.76
9.55
0.2872
-1.90
0.92
-0.86
152.73
37.35
0.1176
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2130.32
-23.42
83.0
59.0
156.0
311.0
5.0
35.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0128828 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
NB69
50 μM
Concentration response
PaperBH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0137874 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
IMR5
20 μM
Concentration response
PaperBH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0155807 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
rrrrrrrr=D-isomer homopolymer of eight arginine residues
Bio-Activity Profile
Antimicrobial Anticancer
SK-N-AS (0% apoptosis at 10 μM)
PaperPubMed PMID: 16568093 PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0172120 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
Bio-Activity Profile
Anticancer
NB69
20 μM
Concentration response
PaperBH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma PMID16568093 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16568093/
RECORD: Rec_0192467 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
FIRST PREV 1 2 3 4 5 6 NEXT LAST
Showing 5 records on this page · Page 3 of 6