Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC529H880N148O160S14

DescriptionStandard

        MKSLLFTLAVFMLLAQLVSGNLYVKRCLNDIGICKKTCKPEEVRSENGWAMCGKHRACCVPADKRSAYPSFCVRAKTTRTSTVTATATTTTTLMSNALMSSMTTMAATPVSPTT
    

Molecular Weight12322.45 Da

Isoelectric Point (pI)9.54

Net Charge (pH 7.0)8.52

Net Charge (pH 7.4) 8.13

Charge Density (pH 7.0) 0.0747

GRAVY Index0.10

Hydrophobic Moment 0.55

Boman Index0.04

Instability Index48.62

Aliphatic Index 71.93

Aromaticity 0.0526

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4940.55

LogP -58.93

H-bond Donors 185.0

H-bond Acceptors 184.0

Rotatable Bonds 404.0

Heavy Atoms 851.0

Ring Count 13.0

Amide Bonds 118.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0117324 VERIFIED: NO

Provenance & Taxonomy

OrganismColobus angolensis palliatus [Animal]

FamilyDefensin

Tax ID336983

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence