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MYP_167726
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Basic Information
CecropinXJ
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
37 amino acids
C185H317N55O46S
Standard
Sequence
RWKIFKKIEKMGRNIRDGIVKAGPAIEVLGSAKAIGK
Physicochemical Analysis
4079.90 Da
10.71
6.76
6.54
0.1827
-0.24
0.91
-0.06
61.88
100.27
0.0541
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1660.98
-12.29
59.0
54.0
146.0
287.0
4.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0105523 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
K. ozaenae
4.62 μM
MIC
PaperProkaryotic expression of cecropin gene isolated from the silk worm Bombyx mori Xinjiang race and antibacterial activity of fusion cecropin
RECORD: Rec_0116783 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Shigella flexneri
3.21 μM
MIC
PMID23500722 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23500722/
RECORD: Rec_0135709 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0142770 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anticancer
D. ribution
2.48 μM
MIC
PaperProkaryotic expression of cecropin gene isolated from the silk worm Bombyx mori Xinjiang race and antibacterial activity of fusion cecropin
RECORD: Rec_0147362 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anticancer
Staphylococcus aureus
1.81
MIC
PMID23500722 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23500722/
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