‹ ›
MYP_167710
← PREVIOUS NEXT → BACK
Basic Information
4330
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Reverse transcriptase inhibition
Standard
20 amino acids
C91H140N26O30S3
Standard
Sequence
KGEAMHGQVDCSPGIWQLDC
Physicochemical Analysis
2174.44 Da
4.54
-2.17
-2.46
-0.1084
-0.40
0.21
0.07
31.38
58.50
0.0500
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
896.23
-9.45
31.0
32.0
70.0
150.0
4.0
21.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0332842 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1
PMID17257575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17257575/
RECORD: Rec_0354891 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
inhibition of reverse transcriptase(DNA-dependent DNA polymerase) activity
6.8 μM
IC50
PaperPubMed PMID: 17257575 PMID17257575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17257575/
RECORD: Rec_0365894 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV-1 Replication inhibition
HIV-1
4 μM
IC50
Mammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min
PaperInhibition of human immunodeficiency virus type-1 reverse transcriptase by a novel peptide derived from the viral integrase. | Oz Gleenberg I, Herschhorn A, Goldgur Y, Hizi A. | Arch Biochem Biophys. 2007 Feb 15;458(2):202-12. | DOI:10.1016/j.abb.2006.12.007 | PMID:17257575 PMID17257575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17257575/
RECORD: Rec_0425370 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1[0-10% RT activity = 30 microM
PMID17257575 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17257575/
FIRST PREV 1 2
Showing 4 records on this page · Page 2 of 2