MYP_167616
Brevinin-1BYa [C18AGL,C24AGL]
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
▸
Antifungal
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
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Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
not Standard
24 amino acids
-
contains X representing unresolved or non-standard residue
FLPILASLAAKFGPKLFXLVTKKX
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0106997
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Allylglycine
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
Human erythrocytes
4 μM
LC50
RECORD: Rec_0131364
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 18,24
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Human hepatocellular carcinoma HepG2
4 μM
LC50
RECORD: Rec_0137541
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Allylglycine
Bio-Activity Profile
Antimicrobial
Anticancer
MDA-MB-231
7 μM
LC50
RECORD: Rec_0139139
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 18,24
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Escherichia coli ATCC 25922
12.5 μM
MIC
RECORD: Rec_0143732
VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Allylglycine
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
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