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MYP_167616
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Basic Information
Brevinin-1BYa [C18AGL,C24AGL]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
24 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FLPILASLAAKFGPKLFXLVTKKX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000310 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 18,24
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus T4/6
2 μM
MIC
PMID21312033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0013986 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
X=Allylglycine
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID21312033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0018555 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 18,24
Bio-Activity Profile
Hemolytic
human erythrocytes
4 μM
Hemolysis
PMID21312033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0082499 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 18,24
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus 127/08
1 μM
MIC
PMID21312033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0085867 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 18,24
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter baumannii NM8
8 μM
MBC
PMID21312033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
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