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MYP_167610
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Basic Information
Ponericin L1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
24 amino acids
C122H215N31O28S
Standard
Sequence
LLKELWTKMKGAGKAVLGKIKGLL
Physicochemical Analysis
2596.27 Da
10.30
4.76
4.54
0.1982
0.29
0.43
0.15
-1.53
134.17
0.0417
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
962.06
-3.41
34.0
34.0
95.0
182.0
2.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0153853 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Insecticidal
P-aeruginosa
>15 μM
MIC
PaperPonericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0197034 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-positive and Gram-negative bacteria
PaperPonericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. J Biol Chem. 2001 May 25;276(21):17823-9. doi: 10.1074/jbc.M100216200. PMID: 11279030. PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0218903 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0235297 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]; Insecta [Animal]
Ponericin
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
RECORD: Rec_0256854 VERIFIED: YES
Provenance & Taxonomy
Pachycondyla goeldii [Animal]
Ponericin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Insecticidal
Bacillus subtilis
0.47 μM
MIC
PaperPonericins, new antibacterial and insecticidal peptides from the venom of the ant Pachycondyla goeldii. PMID11279030 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11279030/
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