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MYP_167609
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ Lipoxygenase Inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Standard
8 amino acids
C43H77N11O10
Standard
Sequence
KVLPVPQK
Physicochemical Analysis
908.14 Da
10.00
1.76
1.55
0.2198
-0.29
0.49
-0.05
94.44
121.25
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
344.57
-1.31
10.0
12.0
28.0
64.0
2.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0055922 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant ROS-reducing
Caco-2 cells
PaperMilk-derived bioactive peptides protect against oxidative stress in a Caco-2 cell model | Tonolo, F. et al. | DOI: 10.1039/c7fo01646h Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0114599 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anti-inflammatory Lipoxygenase Inhibitory
Lipoxygenase
PaperRival S. G., Fornaroli S., Boeriu C. G., Wichers H. J.. Caseins and casein hydrolysates. 1. Lipoxygenase inhibitory properties. J. Agric. Food Chem., 49 (2001), 287-294.
RECORD: Rec_0134621 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Osteoanabolic
Epidermal growth factor receptor
PaperPreparation, identification and screening of anti-osteoporosis milk-derived peptides: intervention effects in osteoporosis rats. Food Bioscience 62:105120 (2024). DOI: 10.1016/j.fbio.2024.105120.
RECORD: Rec_0143636 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperCaseins and Casein Hydrolysates 2 Antioxidative Properties and Relevance to Lipoxygenase Inhibition | Rival, SG. et al. | DOI: 10.1021/jf0003911 Evidence URLhttps://www.uniprot.org/uniprotkb/P02666/entry
RECORD: Rec_0164079 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Lipoxygenase Inhibitory Anti-inflammatory
PaperVariability of hydrolysis of β-, αs1-, and αs2-caseins by 10 strains of Streptococcus thermophilus and resulting bioactive peptides; Caseins and casein hydrolysates. 2. Antioxidative properties and relevance to lipoxygenase inhibition PMID22103626;11170591 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22103626/
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