Peptide Database

Peptide NameDermaseptin-A5

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC382H621N103O127S4

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICEEEKRENEDEEEQEDDEQSEMKRGMWSTIRNVGKSAAKAANLPAKAALGAISEAVGEQ
    

Molecular Weight8816.89 Da

Isoelectric Point (pI)4.61

Net Charge (pH 7.0)-6.48

Net Charge (pH 7.4) -6.74

Charge Density (pH 7.0) -0.0810

GRAVY Index-0.37

Hydrophobic Moment 0.73

Boman Index-0.04

Instability Index59.67

Aliphatic Index 85.50

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3754.24

LogP -37.51

H-bond Donors 128.0

H-bond Acceptors 125.0

Rotatable Bonds 312.0

Heavy Atoms 616.0

Ring Count 6.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0093952 VERIFIED: NO

Provenance & Taxonomy

OrganismAgalychnis annae [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence