Peptide Database

Peptide NamePanitide L5

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC123H196N32O38S6

DescriptionStandard

        QLPICGETCVLGTCYTPGCSCAYPICAR
    

Molecular Weight2923.45 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0107

GRAVY Index0.59

Hydrophobic Moment 0.28

Boman Index0.24

Instability Index21.12

Aliphatic Index 73.21

Aromaticity 0.0714

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1086.32

LogP -12.22

H-bond Donors 43.0

H-bond Acceptors 44.0

Rotatable Bonds 85.0

Heavy Atoms 199.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0108496 VERIFIED: YES

Provenance & Taxonomy

OrganismPanicum laxum [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Other ModsN-terminal pyroglutamate

Bio-Activity Profile

Function

Antimicrobial Cytotoxic

TargetHeLa cells

RECORD: Rec_0383929 VERIFIED: YES