MYP_167547
LP10
Anticancer
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antifungal
Antiparasitic
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Antimalarial
Antiparasitic
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Antiprotozoal
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Antimalarial
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Anti-Plasmodium
Antiparasitic
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General antiparasitic
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Antiparasitic
Binding / Molecular interaction
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Metal-binding / iron acquisition
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Siderophore
Enzyme modulation
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Enzyme inhibition
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ACE inhibition
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ACE inhibitory
Enzyme modulation
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Enzyme inhibition
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Protease inhibition
Enzyme modulation
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Enzyme inhibition
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Tripeptidyl Peptidase II Inhibitory
Other / Curated residual function label
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Generic enzyme inhibition annotation
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Venom / Toxin
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General toxin
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Toxin
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
XX
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0056509
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)6CO
Amidation
Ornithine at 1,2; Ornithine
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
methicillin-resistant Staphylococcus aureus ATCC BAA-1720
>100 μg/mL
RECORD: Rec_0060282
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cyclooctanecarboxylic acid
32630
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
R=CH2C6H5
Bio-Activity Profile
Antimicrobial
Antimalarial
Antiparasitic
Plasmodium falciparum chloroquine resistant
3.54 μM
IC50; Microscopy (Giemsa staining)
RECORD: Rec_0064053
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cyclooctanecarboxylic acid
32630
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
R=H
Bio-Activity Profile
Antimicrobial
Antimalarial
Antiparasitic
Plasmodium falciparum chloroquine sensitive
12.11 μM
IC50; Microscopy (Giemsa staining)
RECORD: Rec_0064603
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protease/Proteasome inhibitor
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Morpholine urea
Vinyl sulfone
Hph=homophenylalanine
Bio-Activity Profile
Antimicrobial
Cysteine protease inhibitor
Antiparasitic
Antimalarial
Plasmodium falciparum Itg2
0.003 μM
IC50; Fluorimetry (fluorescence by hydrolysis of benzyloxycarbonyl-Phe-Arg-7-amino-4-methyl-coumarin measured)
RECORD: Rec_0067016
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
None
l, lauric acid
Bio-Activity Profile
Antiparasitic
Antiplasmodial
Human erythrocytes
100 μM
Hemolysis
Showing 5 records on this page · Page 7 of 35