MYP_167547
Basic Information
LP10
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Antiparasitic Antimalarial
Antiparasitic Antiprotozoal Antimalarial Anti-Plasmodium
Antiparasitic General antiparasitic Antiparasitic
Binding / Molecular interaction Metal-binding / iron acquisition Siderophore
Enzyme modulation Enzyme inhibition ACE inhibition ACE inhibitory
Enzyme modulation Enzyme inhibition Protease inhibition
Enzyme modulation Enzyme inhibition Tripeptidyl Peptidase II Inhibitory
Other / Curated residual function label Generic enzyme inhibition annotation
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
Venom / Toxin General toxin Toxin
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0421891 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Benzyloxycarbonyl
Aldehyde
HPhe- homophenylalanine
Bio-Activity Profile
Antimicrobial Cysteine protease inhibitor Antiparasitic Antimalarial
Plasmodium falciparum D6
0.012 μM
IC50; Microscopy (Giemsa staining)
RECORD: Rec_0422987 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cyclooctanecarboxylic acid
32630
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
R=CH2C6H5
Bio-Activity Profile
Antimicrobial Antimalarial Antiparasitic
Plasmodium falciparum chloroquine sensitive
3.64 μM
IC50; Microscopy (Giemsa staining)
RECORD: Rec_0426203 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cyclopentanecarboxylic acid
32630
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
R=H
Bio-Activity Profile
Antimicrobial Antimalarial Antiparasitic
Plasmodium falciparum chloroquine sensitive
18.44 μM
IC50; Microscopy (Giemsa staining)
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