MYP_167547
LP10
Anticancer
Anticancer
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Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Antimicrobial
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Antibacterial
Antimicrobial
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Antibacterial
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Anti-Gram-negative
Antimicrobial
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Antibacterial
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Anti-Gram-positive
Antimicrobial
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Antifungal
Antiparasitic
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Antimalarial
Antiparasitic
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Antiprotozoal
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Antimalarial
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Anti-Plasmodium
Antiparasitic
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General antiparasitic
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Antiparasitic
Binding / Molecular interaction
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Metal-binding / iron acquisition
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Siderophore
Enzyme modulation
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Enzyme inhibition
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ACE inhibition
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ACE inhibitory
Enzyme modulation
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Enzyme inhibition
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Protease inhibition
Enzyme modulation
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Enzyme inhibition
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Tripeptidyl Peptidase II Inhibitory
Other / Curated residual function label
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Generic enzyme inhibition annotation
Toxicity / Safety
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Blood cell toxicity
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Hemolysis
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Hemolytic
Toxicity / Safety
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Cytotoxicity
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Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxic
Venom / Toxin
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General toxin
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Toxin
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
XX
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0394289
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Morpholine urea
Aldehyde
HPhe- homophenylalanine
Bio-Activity Profile
Antimicrobial
Cysteine protease inhibitor
Antiparasitic
Antimalarial
Plasmodium falciparum HB3
0.0026 μM
IC50; Microscopy (Giemsa staining)
RECORD: Rec_0402327
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)6CO
Amidation
Ornithine at 1,2; Ornithine
Bio-Activity Profile
Hemolytic
human red blood cells
1000 μg/mL
Hemolysis
RECORD: Rec_0405551
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Benzyloxycarbonyl
Aldehyde
HPhe- homophenylalanine
Bio-Activity Profile
Antimicrobial
Cysteine protease inhibitor
Antiparasitic
Antimalarial
Plasmodium falciparum W2
0.002 μM
IC50; Flourimetry (Hydrolysis of the fluorogenic substrate)
RECORD: Rec_0408164
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cyclooctanecarboxylic acid
32630
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
R=CH(CH3)2
Bio-Activity Profile
Antimicrobial
Antimalarial
Antiparasitic
Plasmodium falciparum chloroquine sensitive
6.14 μM
IC50; Microscopy (Giemsa staining)
RECORD: Rec_0408646
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cyclooctanecarboxylic acid
32630
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
R=CH2CH(CH3)2
Bio-Activity Profile
Antimicrobial
Antimalarial
Antiparasitic
Plasmodium falciparum chloroquine sensitive
3.87 μM
IC50; Microscopy (Giemsa staining)
Showing 5 records on this page · Page 33 of 35