MYP_167547
Basic Information
LP10
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-negative
Antimicrobial Antibacterial Anti-Gram-positive
Antimicrobial Antifungal
Antiparasitic Antimalarial
Antiparasitic Antiprotozoal Antimalarial Anti-Plasmodium
Antiparasitic General antiparasitic Antiparasitic
Binding / Molecular interaction Metal-binding / iron acquisition Siderophore
Enzyme modulation Enzyme inhibition ACE inhibition ACE inhibitory
Enzyme modulation Enzyme inhibition Protease inhibition
Enzyme modulation Enzyme inhibition Tripeptidyl Peptidase II Inhibitory
Other / Curated residual function label Generic enzyme inhibition annotation
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
Venom / Toxin General toxin Toxin
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0355201 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)16CO
Amidation
Ornithine at 1,2; Ornithine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis MTCC 2763
50 μg/mL
RECORD: Rec_0355437 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)16CO
Amidation
Ornithine at 1,2; Ornithine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 24433
12.5 μg/mL
RECORD: Rec_0357773 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Benzyloxycarbonyl
Aldehyde
HPhe- homophenylalanine
Bio-Activity Profile
Antimicrobial Cysteine protease inhibitor Antiparasitic Antimalarial
Plasmodium falciparum HB3
0.016 μM
IC50; Microscopy (Giemsa staining)
RECORD: Rec_0367196 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Benzyloxycarbonyl
Aldehyde
HPhe- homophenylalanine
Bio-Activity Profile
Antimicrobial Cysteine protease inhibitor Antiparasitic Antimalarial
Plasmodium falciparum ItG
0.019 μM
IC50; Microscopy (Giemsa staining)
RECORD: Rec_0367642 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)14CO
Amidation
Ornithine at 1,2; Ornithine
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC 24433
6.25 μg/mL
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