MYP_167547
LP10
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
▸
Cytotoxic
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antimicrobial
▸
Antifungal
Antiparasitic
▸
Antimalarial
Antiparasitic
▸
Antiprotozoal
▸
Antimalarial
▸
Anti-Plasmodium
Antiparasitic
▸
General antiparasitic
▸
Antiparasitic
Binding / Molecular interaction
▸
Metal-binding / iron acquisition
▸
Siderophore
Enzyme modulation
▸
Enzyme inhibition
▸
ACE inhibition
▸
ACE inhibitory
Enzyme modulation
▸
Enzyme inhibition
▸
Protease inhibition
Enzyme modulation
▸
Enzyme inhibition
▸
Tripeptidyl Peptidase II Inhibitory
Other / Curated residual function label
▸
Generic enzyme inhibition annotation
Toxicity / Safety
▸
Blood cell toxicity
▸
Hemolysis
▸
Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Cytotoxic
Venom / Toxin
▸
General toxin
▸
Toxic
Venom / Toxin
▸
General toxin
▸
Toxin
not Standard
2 amino acids
-
contains X representing unresolved or non-standard residue
XX
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
RECORD: Rec_0319158
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
pyrrolidine--carboxylic acid
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
R=C16H28O5N2
Bio-Activity Profile
Antimicrobial
Antimalarial
Antiparasitic
Plasmodium falciparum chloroquine sensitive
14.56 μM
IC50; Microscopy (Giemsa staining)
RECORD: Rec_0323362
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
cyclooctanecarboxylic acid
32630
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
R=CH2C6H5
Bio-Activity Profile
Antimicrobial
Antimalarial
Antiparasitic
Plasmodium berghei
100 mg/kg
Microscopy (Giemsa staining)
RECORD: Rec_0326083
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
ornithine at 1,2
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Anti-Gram-negative
Acinetobacter baumannii
56.8
MIC
RECORD: Rec_0330267
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
CH3(CH2)10CO
Amidation
Ornithine at 1,2; Ornithine
Bio-Activity Profile
Antimicrobial
Antibacterial
Antifungal
Anti-Gram-positive
Anti-Gram-negative
Cryptococcus neoformans ATCC 2344
50 μg/mL
RECORD: Rec_0336391
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
KKWβ2,2WKK
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
(2,2-di(4-[trifluoromethyl]benzyl)-3-amino-propionic acid)
Bio-Activity Profile
Anticancer
Cytotoxic
Ramos
26±2 μM
IC50
Showing 5 records on this page · Page 28 of 35