Peptide Database

Peptide NameConotoxin-3

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC112H175N31O40S6

DescriptionStandard

        CESYGKPCGIYNDCCNACDPAKKTCT
    

Molecular Weight2788.16 Da

Isoelectric Point (pI)6.08

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.60

Charge Density (pH 7.0) -0.0115

GRAVY Index-0.57

Hydrophobic Moment 0.42

Boman Index-0.11

Instability Index45.68

Aliphatic Index 22.69

Aromaticity 0.0769

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1150.53

LogP -15.94

H-bond Donors 44.0

H-bond Acceptors 46.0

Rotatable Bonds 87.0

Heavy Atoms 189.0

Ring Count 4.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125451 VERIFIED: NO

Provenance & Taxonomy

OrganismConus striatus [Animal]; Conus striolatus [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 8-18; 14-25

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0391256 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic