Peptide Database

Peptide NameBrentuximab vedotin

Function Ontology

Anticancer

Standard StatusStandard

Sequence Length243 amino acids

Chemical FormulaC1170H1782N292O357S8

DescriptionStandard

        QIQLQQSGPEVVKPGASVKISCKASGYTFTDYYITWVKQKPGQGLEWIGWIYPGSGNTKYNEKFKGKATLTVDTSSSTAFMQLSSLTSEDTAVYFCANYGNYWFAYWGQGTQVTVSAASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLF
    

Molecular Weight25906.93 Da

Isoelectric Point (pI)8.74

Net Charge (pH 7.0)4.95

Net Charge (pH 7.4) 4.43

Charge Density (pH 7.0) 0.0204

GRAVY Index-0.17

Hydrophobic Moment 0.53

Boman Index0.13

Instability Index34.58

Aliphatic Index 66.54

Aromaticity 0.1152

Extinction Coeff. Reduced 50880.00

Extinction Coeff. Oxidized 51255.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0410033 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyAntibody-drug conjugate

Tax ID9606

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitynoncanonical stereochemical or chemical modification [Modified]

Other ModsMMAE drug conjugation

Bio-Activity Profile

Function

Anticancer Monoclonal antibody

Half-LifeTerminal half-life is 4-6 d