Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC370H576N104O107S11

DescriptionStandard

        MKNFSAFALFLILSICLFTGLEGRHSDEQCSDPFVLNGRCTARRCALQCLARHKHIDVGECFSEPPNTCMCIYPCD
    

Molecular Weight8545.88 Da

Isoelectric Point (pI)6.24

Net Charge (pH 7.0)-1.31

Net Charge (pH 7.4) -1.83

Charge Density (pH 7.0) -0.0173

GRAVY Index0.11

Hydrophobic Moment 0.47

Boman Index0.06

Instability Index63.18

Aliphatic Index 75.79

Aromaticity 0.0921

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3354.16

LogP -33.36

H-bond Donors 124.0

H-bond Acceptors 120.0

Rotatable Bonds 276.0

Heavy Atoms 592.0

Ring Count 14.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216364 VERIFIED: NO

Provenance & Taxonomy

OrganismAquilegia coerulea [Plant]

FamilyDEFL family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal