Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length471 amino acids

Chemical FormulaC2319H3744N580O677S24

DescriptionStandard

        MFLCLALLTLLPATVSISPGVKVELTQKGIDYGRQLGIASIQSKLKTIRIPDISGTTNVPAVGKVKYSLSGLQLLDVGLPKSALDLVTGSGVRLSIGDAYMKLRGNWKVKYLKFITDHGSFDLNVNGLTITTSIKIDSDDTGRPAVSTISCSASVGSLKIQCHGGDKWMCDLFKDLLEKFGRKSLEKQICPLVQTAVSELNPELKTMNVLAKVDQYAEIEYSMVSSPVISNTSLVLNLKGEFYNIGKHQEPPFTATDFSMPTEANNMMYMGISAFTVNSAAFVYTTAGILSLYITDDMIPKSSPFRLTTKSFGIFVPQVEEKFPDLPMKLLVKAVKSPTVTFEPDNMTIQAAATVTAYAIQPNATLSPLFVLSLESSVSGRVFVSGIKLAGEVTLQKMNMTLVTSYVGDFRVESLDKIFKMVINLGILPKLNERLAQGYPLPMIGKMKLVSSQLHILKDYMLIGTDVQFMG
    

Molecular Weight51351.57 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)5.82

Net Charge (pH 7.4) 5.21

Charge Density (pH 7.0) 0.0124

GRAVY Index0.19

Hydrophobic Moment 0.79

Boman Index0.15

Instability Index33.24

Aliphatic Index 102.40

Aromaticity 0.0764

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 32110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384452 VERIFIED: NO

Provenance & Taxonomy

OrganismSalarias fasciatus (Jewelled blenny) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria