Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC441H696N130O134S11

DescriptionStandard

        MKLTRVALAAAVVITCVCFLQTAAVPFTQQTEDEHHVESEAPQENQHLTETSQEQTNPLAFFRVKRQSHLSLCRYCCNCCRNKGCGYCCKF
    

Molecular Weight10315.75 Da

Isoelectric Point (pI)7.53

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.18

Charge Density (pH 7.0) 0.0084

GRAVY Index-0.24

Hydrophobic Moment 0.66

Boman Index-0.05

Instability Index48.05

Aliphatic Index 65.38

Aromaticity 0.0769

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4282.95

LogP -49.04

H-bond Donors 156.0

H-bond Acceptors 150.0

Rotatable Bonds 339.0

Heavy Atoms 716.0

Ring Count 14.0

Amide Bonds 102.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0402931 VERIFIED: YES

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyHepcidin

Tax ID7962

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal