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MYP_167418
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Basic Information
Cyclosaplin
Anticancer
Anticancer ▸ Apoptosis induction
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
8 amino acids
C33H60N14O12S
Standard
Sequence
RLGDGCTR
Physicochemical Analysis
876.98 Da
8.25
0.75
0.53
0.0939
-0.96
0.82
-0.46
49.50
48.75
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
448.35
-6.59
18.0
14.0
29.0
60.0
0.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184579 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0313137 VERIFIED: YES
Provenance & Taxonomy
somatic seedlings of sandalwood [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231
2.06 μg/mL
IC50
PaperPubMed PMID: 24503375 PMID24503375 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24503375/
RECORD: Rec_0380552 VERIFIED: YES
Provenance & Taxonomy
somatic seedlings of sandalwood [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 24503375 PMID24503375 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24503375/
RECORD: Rec_0395601 VERIFIED: YES
Provenance & Taxonomy
Santalum album [Plant]
Cyclic Peptide
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic Hemolytic
Human breast adenocarcinoma MDA-MB-231
2.06 μg/mL
IC50
PaperPubMed PMID 24503375 PMID24503375 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24503375/
RECORD: Rec_0400347 VERIFIED: YES
Provenance & Taxonomy
somatic seedlings of sandalwood [other]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 24503375 PMID24503375 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24503375/
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