Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC733H1159N195O215S11

DescriptionStandard

        METQRASLCLGRWSLWLLLLGLVVPSASAQALSYREAVLRAVDRLNEQSSEANLYRLLELDQPPKADEDPGTPKPVSFTVKETVCPRPTWRPPELCDFKENGRVKQCVGTVTLDQIKDPLDITCNELCWAWLVTLECPCYLWACVC
    

Molecular Weight16495.94 Da

Isoelectric Point (pI)4.89

Net Charge (pH 7.0)-4.57

Net Charge (pH 7.4) -4.97

Charge Density (pH 7.0) -0.0313

GRAVY Index-0.10

Hydrophobic Moment 0.77

Boman Index0.02

Instability Index37.07

Aliphatic Index 94.79

Aromaticity 0.0753

Extinction Coeff. Reduced 37470.00

Extinction Coeff. Oxidized 38095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6529.50

LogP -56.26

H-bond Donors 233.0

H-bond Acceptors 222.0

Rotatable Bonds 526.0

Heavy Atoms 1154.0

Ring Count 29.0

Amide Bonds 155.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246075 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal