Peptide Database

Peptide NameRCG-P2G4

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC102H187N53O28

DescriptionStandard

        RPRGRRGSRPSGAERRRRRAAAA
    

Molecular Weight2603.91 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.76

Net Charge (pH 7.4) 8.56

Charge Density (pH 7.0) 0.3810

GRAVY Index-1.98

Hydrophobic Moment 0.51

Boman Index-0.94

Instability Index153.23

Aliphatic Index 21.74

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1382.70

LogP -21.45

H-bond Donors 55.0

H-bond Acceptors 37.0

Rotatable Bonds 88.0

Heavy Atoms 183.0

Ring Count 2.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0258660 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1 Bal:inhibition of virus replication in PM1-CCR5 cells

Activity10 μM

MethodEC50

RECORD: Rec_0292502 VERIFIED: YES