Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC242H387N65O81S6

DescriptionStandard

        MKNTTNEMLELIQEVSLDELDQVIGGMGKGAVGTISHECRYNSWAFLATCCS
    

Molecular Weight5695.44 Da

Isoelectric Point (pI)4.49

Net Charge (pH 7.0)-4.43

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.0852

GRAVY Index-0.02

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index5.86

Aliphatic Index 82.50

Aromaticity 0.0577

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2364.45

LogP -25.95

H-bond Donors 84.0

H-bond Acceptors 84.0

Rotatable Bonds 193.0

Heavy Atoms 394.0

Ring Count 5.0

Amide Bonds 56.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237479 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus mutans [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence