Peptide Database

Peptide NameGHaR8R (variant of temporin-GHaR)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC75H125N23O15

DescriptionStandard

        FLQRIIGRLGRLF
    

Molecular Weight1588.94 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.56

Charge Density (pH 7.0) 0.2123

GRAVY Index0.63

Hydrophobic Moment 0.93

Boman Index0.06

Instability Index34.31

Aliphatic Index 150.00

Aromaticity 0.1538

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 641.31

LogP -2.75

H-bond Donors 24.0

H-bond Acceptors 18.0

Rotatable Bonds 54.0

Heavy Atoms 113.0

Ring Count 2.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0364360 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsMethicillin-resistant Staphylococcus aureus

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetmethicillin-resistant Staphylococcus aureus-4

Activity6.2 μM

MethodMIC

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