Peptide Database

Peptide NameOrcokinin-2

Function Ontology

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Invertebrate neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length19 amino acids

Chemical FormulaC104H130N24O31

DescriptionStandard

        WYGHGDFDEIDNVGWPGFT
    

Molecular Weight2212.29 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-4.15

Net Charge (pH 7.4) -4.41

Charge Density (pH 7.0) -0.2183

GRAVY Index-0.71

Hydrophobic Moment 0.41

Boman Index0.22

Instability Index14.24

Aliphatic Index 35.79

Aromaticity 0.2632

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 871.34

LogP -5.75

H-bond Donors 29.0

H-bond Acceptors 28.0

Rotatable Bonds 63.0

Heavy Atoms 159.0

Ring Count 9.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014658 VERIFIED: YES

Provenance & Taxonomy

OrganismIxodes scapularis [Animal]

FamilyOrcokinin

Tax ID6945

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Invertebrate neuropeptide

RECORD: Rec_0095071 VERIFIED: NO

Provenance & Taxonomy

OrganismIxodes scapularis [Animal]

Tax ID6945

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0139330 VERIFIED: YES

Provenance & Taxonomy

OrganismIxodes scapularis [Animal]

FamilyOrcokinin

Tax ID6945

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Myotropic

Half-LifeMammalian: 2.8 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0381603 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/